Update: The Soyuz MS-10 crew failed to reach orbit. The crew is safe. More information can be found here.
Soyuz MS-10 is scheduled to launch two members of the Expedition 57 crew to the International Space Station: Russian cosmonaut Aleksey Ovchinin and NASA astronaut Nick Hague. Liftoff at Baikonur Cosmodrome is expected at about 8:40 UTC Oct 11, 2018, with a docking to the Poisk module some four orbits later at 14:44 UTC.
This will be Ovchinin's second spaceflight and Hague's first. Ovchinin first flew to the ISS in 2016 as part of Expedition 47 and 48. Hague is a member of NASA's class of 2013 astronaut class and is expected to be the first of his group to fly.
A second cosmonaut, Nikolai Tikhonov, was originally manifested to fly on Soyuz MS-10. However, because of delays in the launch of the Nauka Multipurpose Laboratory Module, now planned for November 2019, the cosmonaut was bumped to the Soyuz MS-14 mission scheduled around the same time.
On July 13, 2018, the completed spacecraft was delivered to a vacuum chamber for several days of leak tests, according to Roscosmos. The next steps will be for engineers to finish the assembly of the Soyuz-FG carrier rocket before encapsulating and mating the Soyuz MS-10 spacecraft to the top of the booster.
Rollout to launch pad 1/5 via rail should occur several days before launch. There it will be raised from its horizontal position to vertical.
After liftoff, the spacecraft is expected to autonomously make its way to the ISS over four orbits. This fast-rendezvous profile will culminate in a docking with the Poisk module on the Russian side of the space station.
Ovchinin and Hague are expected to remain at the outpost for about seven months before undocking and landing in Kazakhstan on April 16, 2019. During that time, the duo will form the first part of Expedition 58 when the Soyuz MS-09 crew leaves in December 2018.